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Protease-activated receptor (PAR)-2 is required for PAR-1 signalling in pulmonary fibrosis

Idiopathic pulmonary fibrosis is the most devastating diffuse fibrosing lung disease of unknown aetiology. Compelling evidence suggests that both protease-activated receptor (PAR)-1 and PAR-2 participate in the development of pulmonary fibrosis. Previous studies have shown that bleomycin-induced lun...

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Detalles Bibliográficos
Autores principales: Lin, Cong, von der Thüsen, Jan, Daalhuisen, Joost, ten Brink, Marieke, Crestani, Bruno, van der Poll, Tom, Borensztajn, Keren, Spek, C Arnold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459848/
https://www.ncbi.nlm.nih.gov/pubmed/25689283
http://dx.doi.org/10.1111/jcmm.12520