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DICER1 regulated let-7 expression levels in p53-induced cancer repression requires cyclin D1
Let-7 miRNAs act as tumour suppressors by directly binding to the 3′UTRs of downstream gene products. The regulatory role of let-7 in downstream gene expression has gained much interest in the cancer research community, as it controls multiple biological functions and determines cell fates. For exam...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459849/ https://www.ncbi.nlm.nih.gov/pubmed/25702703 http://dx.doi.org/10.1111/jcmm.12522 |