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High glucose-induced intestinal epithelial barrier damage is aggravated by syndecan-1 destruction and heparanase overexpression

Syndecan-1 (Sdc1) and its endo-beta-d-glucuronidase heparanase (HPSE) are implicated in maintenance of intestinal epithelial barrier (IEB), but their alterations and roles in high-glucose/hyperglycaemia (HG) conditions have not been fully investigated. This study aimed to determine the expression pa...

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Detalles Bibliográficos
Autores principales: Qing, Qing, Zhang, Shaoheng, Chen, Ye, Li, Runhua, Mao, Hua, Chen, Qikui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459850/
https://www.ncbi.nlm.nih.gov/pubmed/25702768
http://dx.doi.org/10.1111/jcmm.12523