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Endogenous and Uric Acid-Induced Activation of NLRP3 Inflammasome in Pregnant Women with Preeclampsia

Preeclampsia (PE) is a specific syndrome of pregnancy, characterized by hypertension and proteinuria. This pathology is associated with hyperuricemia and elevated serum levels of inflammatory cytokines. Uric acid crystals may activate an intracellular complex called inflammasome, which is important...

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Detalles Bibliográficos
Autores principales: Matias, Mariana Leticia, Romão, Mariana, Weel, Ingrid Cristina, Ribeiro, Vanessa Rocha, Nunes, Priscila Rezeck, Borges, Vera Therezinha, Araújo, João Pessoa, Peraçoli, José Carlos, de Oliveira, Leandro, Peraçoli, Maria Terezinha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459873/
https://www.ncbi.nlm.nih.gov/pubmed/26053021
http://dx.doi.org/10.1371/journal.pone.0129095