Matriptase promotes inflammatory cell accumulation and progression of established epidermal tumors

Deregulation of matriptase is a consistent feature of human epithelial cancers and correlates with poor disease outcome. We have previously shown that matriptase promotes multi-stage squamous cell carcinogenesis in transgenic mice through dual activation of pro-hepatocyte growth factor-cMet-Akt-mTor...

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Detalles Bibliográficos
Autores principales: Sales, Katiuchia Uzzun, Friis, Stine, Abusleme, Loreto, Moutsopoulos, Niki M., Bugge, Thomas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459940/
https://www.ncbi.nlm.nih.gov/pubmed/25486433
http://dx.doi.org/10.1038/onc.2014.391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459940/
https://www.ncbi.nlm.nih.gov/pubmed/25486433
http://dx.doi.org/10.1038/onc.2014.391

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