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Matriptase promotes inflammatory cell accumulation and progression of established epidermal tumors
Deregulation of matriptase is a consistent feature of human epithelial cancers and correlates with poor disease outcome. We have previously shown that matriptase promotes multi-stage squamous cell carcinogenesis in transgenic mice through dual activation of pro-hepatocyte growth factor-cMet-Akt-mTor...
Autores principales: | Sales, Katiuchia Uzzun, Friis, Stine, Abusleme, Loreto, Moutsopoulos, Niki M., Bugge, Thomas H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459940/ https://www.ncbi.nlm.nih.gov/pubmed/25486433 http://dx.doi.org/10.1038/onc.2014.391 |
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