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Targeting Type Iγ Phosphatidylinositol Phosphate Kinase Inhibits Breast Cancer Metastasis
Most deaths from breast cancer are caused by metastasis, a complex behavior of cancer cells involving migration, invasion, survival, and microenvironment manipulation. Type Iγ phosphatidylinositol phosphate kinase (PIPKIγ) regulates focal adhesion assembly, and its phosphorylation at Y639 is critica...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459944/ https://www.ncbi.nlm.nih.gov/pubmed/25486426 http://dx.doi.org/10.1038/onc.2014.393 |