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Targeting Type Iγ Phosphatidylinositol Phosphate Kinase Inhibits Breast Cancer Metastasis

Most deaths from breast cancer are caused by metastasis, a complex behavior of cancer cells involving migration, invasion, survival, and microenvironment manipulation. Type Iγ phosphatidylinositol phosphate kinase (PIPKIγ) regulates focal adhesion assembly, and its phosphorylation at Y639 is critica...

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Detalles Bibliográficos
Autores principales: Chen, Chunhua, Wang, Xiangling, Xiong, Xunhao, Liu, Qingbo, Huang, Yan, Xu, Qingwen, Hu, Jinghua, Ge, Gaoxiang, Ling, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459944/
https://www.ncbi.nlm.nih.gov/pubmed/25486426
http://dx.doi.org/10.1038/onc.2014.393