Casein Kinase 2 prevents mesenchymal transformation by maintaining Foxc2 in the cytoplasm

Nuclear Foxc2 is a transcriptional regulator of mesenchymal transformation during developmental EMT and has been associated with EMT in malignant epithelia. Our laboratory has shown that in normal epithelial cells Foxc2 is maintained in the cytoplasm where it promotes an epithelial phenotype. The Fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Golden, Diana, Cantley, Lloyd G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459945/
https://www.ncbi.nlm.nih.gov/pubmed/25486430
http://dx.doi.org/10.1038/onc.2014.395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459945/
https://www.ncbi.nlm.nih.gov/pubmed/25486430
http://dx.doi.org/10.1038/onc.2014.395

Ejemplares similares