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Dissecting the contribution of knee joint NGF to spinal nociceptive sensitization in a model of OA pain in the rat

OBJECTIVE: Although analgesic approaches targeting nerve growth factor (NGF) for the treatment of osteoarthritis (OA) pain remain of clinical interest, neurophysiological mechanisms by which NGF contribute to OA pain remain unclear. We investigated the impact of local elevation of knee joint NGF on...

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Detalles Bibliográficos
Autores principales: Sagar, D.R., Nwosu, L., Walsh, D.A., Chapman, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W.B. Saunders For The Osteoarthritis Research Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459966/
https://www.ncbi.nlm.nih.gov/pubmed/25623624
http://dx.doi.org/10.1016/j.joca.2015.01.010