Deletion of Fifteen Open Reading Frames from Modified Vaccinia Virus Ankara Fails to Improve Immunogenicity

Modified vaccinia virus Ankara (MVA) is a highly attenuated strain of vaccinia virus, which has been used as a recombinant vaccine vector in many vaccine development programmes. The loss of many immunosuppressive and host-range genes resulted in a safe and immunogenic vaccine vector. However it stil...

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Detalles Bibliográficos
Autores principales: Alharbi, Naif Khalaf, Spencer, Alexandra J., Hill, Adrian V. S., Gilbert, Sarah C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459983/
https://www.ncbi.nlm.nih.gov/pubmed/26053118
http://dx.doi.org/10.1371/journal.pone.0128626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459983/
https://www.ncbi.nlm.nih.gov/pubmed/26053118
http://dx.doi.org/10.1371/journal.pone.0128626

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