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Epigenetic Modifications of the PGC-1α Promoter during Exercise Induced Expression in Mice

The transcriptional coactivator, PGC-1α, is known for its role in mitochondrial biogenesis. Although originally thought to exist as a single protein isoform, recent studies have identified additional promoters which produce multiple mRNA transcripts. One of these promoters (promoter B), approximatel...

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Detalles Bibliográficos
Autores principales: Lochmann, Timothy L., Thomas, Ravindar R., Bennett, James P., Taylor, Shirley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460005/
https://www.ncbi.nlm.nih.gov/pubmed/26053857
http://dx.doi.org/10.1371/journal.pone.0129647