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Thymic Atrophy and Apoptosis of CD4(+)CD8(+) Thymocytes in the Cuprizone Model of Multiple Sclerosis
Previous studies on the degenerative animal model of multiple sclerosis suggested that the copper-chelator cuprizone might directly suppress T-cell functions. Peripheral T-cell function in the cuprizone model has already been explored; therefore, in the present study, we investigated, for the first...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460035/ https://www.ncbi.nlm.nih.gov/pubmed/26053248 http://dx.doi.org/10.1371/journal.pone.0129217 |