Inhibition of Glycoprotein VI Clustering by Collagen as a Mechanism of Inhibiting Collagen-Induced Platelet Responses: The Example of Losartan

Exposure of platelets to collagen triggers the formation of a platelet clot. Pharmacological agents capable of inhibiting platelet activation by collagen are thus of potential therapeutic interest. Thrombus formation is initiated by the interaction of the GPIb-V-IX complex with collagen-bound vWF, w...

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Detalles Bibliográficos
Autores principales: Jiang, Peng, Loyau, Stéphane, Tchitchinadze, Maria, Ropers, Jacques, Jondeau, Guillaume, Jandrot-Perrus, Martine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460036/
https://www.ncbi.nlm.nih.gov/pubmed/26052700
http://dx.doi.org/10.1371/journal.pone.0128744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460036/
https://www.ncbi.nlm.nih.gov/pubmed/26052700
http://dx.doi.org/10.1371/journal.pone.0128744

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