BRAF Mutations in Canine Cancers

Activating mutations of the BRAF gene lead to constitutive activation of the MAPK pathway. Although many human cancers carry the mutated BRAF gene, this mutation has not yet been characterized in canine cancers. As human and canine cancers share molecular abnormalities, we hypothesized that BRAF gen...

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Detalles Bibliográficos
Autores principales: Mochizuki, Hiroyuki, Kennedy, Katherine, Shapiro, Susan G., Breen, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460039/
https://www.ncbi.nlm.nih.gov/pubmed/26053201
http://dx.doi.org/10.1371/journal.pone.0129534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460039/
https://www.ncbi.nlm.nih.gov/pubmed/26053201
http://dx.doi.org/10.1371/journal.pone.0129534

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