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Fibroblasts Influence Survival and Therapeutic Response in a 3D Co-Culture Model

In recent years, evidence has indicated that the tumor microenvironment (TME) plays a significant role in tumor progression. Fibroblasts represent an abundant cell population in the TME and produce several growth factors and cytokines. Fibroblasts generate a suitable niche for tumor cell survival an...

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Detalles Bibliográficos
Autores principales: Majety, Meher, Pradel, Leon P., Gies, Manuela, Ries, Carola H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460080/
https://www.ncbi.nlm.nih.gov/pubmed/26053043
http://dx.doi.org/10.1371/journal.pone.0127948