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Fibroblasts Influence Survival and Therapeutic Response in a 3D Co-Culture Model
In recent years, evidence has indicated that the tumor microenvironment (TME) plays a significant role in tumor progression. Fibroblasts represent an abundant cell population in the TME and produce several growth factors and cytokines. Fibroblasts generate a suitable niche for tumor cell survival an...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460080/ https://www.ncbi.nlm.nih.gov/pubmed/26053043 http://dx.doi.org/10.1371/journal.pone.0127948 |