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Developmental Expression and Hypoxic Induction of Hypoxia Inducible Transcription Factors in the Zebrafish
The hypoxia inducible transcription factor (HIF) has been shown to coordinate the hypoxic response of vertebrates and is expressed in three different isoforms, HIF-1α, HIF-2α and HIF-3α. Knock down of either Hif-1α or Hif-2α in mice results in lethality in embryonic or perinatal stages, suggesting t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460093/ https://www.ncbi.nlm.nih.gov/pubmed/26052946 http://dx.doi.org/10.1371/journal.pone.0128938 |