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Developmental Expression and Hypoxic Induction of Hypoxia Inducible Transcription Factors in the Zebrafish

The hypoxia inducible transcription factor (HIF) has been shown to coordinate the hypoxic response of vertebrates and is expressed in three different isoforms, HIF-1α, HIF-2α and HIF-3α. Knock down of either Hif-1α or Hif-2α in mice results in lethality in embryonic or perinatal stages, suggesting t...

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Detalles Bibliográficos
Autores principales: Köblitz, Louise, Fiechtner, Birgit, Baus, Katharina, Lussnig, Rebecca, Pelster, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460093/
https://www.ncbi.nlm.nih.gov/pubmed/26052946
http://dx.doi.org/10.1371/journal.pone.0128938