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From Heuristic to Mathematical Modeling of Drugs Dissolution Profiles: Application of Artificial Neural Networks and Genetic Programming

The purpose of this work was to develop a mathematical model of the drug dissolution (Q) from the solid lipid extrudates based on the empirical approach. Artificial neural networks (ANNs) and genetic programming (GP) tools were used. Sensitivity analysis of ANNs provided reduction of the original in...

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Detalles Bibliográficos
Autores principales: Mendyk, Aleksander, Güres, Sinan, Jachowicz, Renata, Szlęk, Jakub, Polak, Sebastian, Wiśniowska, Barbara, Kleinebudde, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460208/
https://www.ncbi.nlm.nih.gov/pubmed/26101544
http://dx.doi.org/10.1155/2015/863874