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From Heuristic to Mathematical Modeling of Drugs Dissolution Profiles: Application of Artificial Neural Networks and Genetic Programming
The purpose of this work was to develop a mathematical model of the drug dissolution (Q) from the solid lipid extrudates based on the empirical approach. Artificial neural networks (ANNs) and genetic programming (GP) tools were used. Sensitivity analysis of ANNs provided reduction of the original in...
Autores principales: | Mendyk, Aleksander, Güres, Sinan, Jachowicz, Renata, Szlęk, Jakub, Polak, Sebastian, Wiśniowska, Barbara, Kleinebudde, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460208/ https://www.ncbi.nlm.nih.gov/pubmed/26101544 http://dx.doi.org/10.1155/2015/863874 |
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