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Gender differences in pharmacokinetics and pharmacodynamics of methadone substitution therapy

Gender-related differences in the pharmacological effects of drug are an emerging topic. This review examines gender differences in both pharmacokinetic and pharmacodynamic aspects of methadone, a long-acting opioid agonist that is prescribed as a treatment for opioid dependence and the management o...

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Detalles Bibliográficos
Autores principales: Graziani, Manuela, Nisticò, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460328/
https://www.ncbi.nlm.nih.gov/pubmed/26106330
http://dx.doi.org/10.3389/fphar.2015.00122