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Gender differences in pharmacokinetics and pharmacodynamics of methadone substitution therapy
Gender-related differences in the pharmacological effects of drug are an emerging topic. This review examines gender differences in both pharmacokinetic and pharmacodynamic aspects of methadone, a long-acting opioid agonist that is prescribed as a treatment for opioid dependence and the management o...
Autores principales: | Graziani, Manuela, Nisticò, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460328/ https://www.ncbi.nlm.nih.gov/pubmed/26106330 http://dx.doi.org/10.3389/fphar.2015.00122 |
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