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Type II collagen and glycosaminoglycan expression induction in primary human chondrocyte by TGF-β1

BACKGROUND: A localized non-surgical delivery of allogeneic human chondrocytes (hChonJ) with irradiated genetically modified chondrocytes (hChonJb#7) expressing transforming growth factor-β1 (TGF-β1) showed efficacy in regenerating cartilage tissue in our pre-clinical studies and human Phase I and I...

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Detalles Bibliográficos
Autores principales: Yoon, Hyun Joo, Kim, Suk Bum, Somaiya, Dhara, Noh, Moon Jong, Choi, Kyoung-Baek, Lim, Chae-Lyul, Lee, Hyeon-Youl, Lee, Yeon-Ju, Yi, Youngsuk, Lee, Kwan Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460646/
https://www.ncbi.nlm.nih.gov/pubmed/26059549
http://dx.doi.org/10.1186/s12891-015-0599-x