Structural investigations of T854A mutation in EGFR and identification of novel inhibitors using structure activity relationships

BACKGROUND: The epidermal growth factor receptor (EGFR) is a member of the ErbB family that is involved in a number of processes responsible for cancer development and progression such as angiogenesis, apoptosis, cell proliferation and metastatic spread. Malfunction in activation of protein tyrosine...

Descripción completa

Detalles Bibliográficos
Autores principales: Goyal, Sukriti, Jamal, Salma, Shanker, Asheesh, Grover, Abhinav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460657/
https://www.ncbi.nlm.nih.gov/pubmed/26041145
http://dx.doi.org/10.1186/1471-2164-16-S5-S8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460657/
https://www.ncbi.nlm.nih.gov/pubmed/26041145
http://dx.doi.org/10.1186/1471-2164-16-S5-S8

Ejemplares similares