CMTX1 patients’ cells present genomic instability corrected by CamKII inhibitors

BACKGROUND: We previously described that fibroblasts from animal models of CMTX1 present genomic instability and poor connexon activity. In vivo, these transgenic mice present motor deficits. This phenotype could be significantly reverted by treatment with (CamKII) inhibitors. The objective of this...

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Detalles Bibliográficos
Autores principales: Saleh, Mones, Burkhardt, Gess, Benoit, Bordignon, Alexandre, Altié, Peter, Young, Frederic, Bihel, Marc, Fraterno, Franck, Peiretti, Michel, Fontes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460704/
https://www.ncbi.nlm.nih.gov/pubmed/25947624
http://dx.doi.org/10.1186/s13023-015-0270-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460704/
https://www.ncbi.nlm.nih.gov/pubmed/25947624
http://dx.doi.org/10.1186/s13023-015-0270-5

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