Identification of epigenetic modifications that contribute to pathogenesis in therapy-related AML: Effective integration of genome-wide histone modification with transcriptional profiles

BACKGROUND: Therapy-related, secondary acute myeloid leukemia (t-AML) is an increasingly frequent complication of intensive chemotherapy. This malignancy is often characterized by abnormalities of chromosome 7, including large deletions or chromosomal loss. A variety of studies suggest that decrease...

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Detalles Bibliográficos
Autores principales: Yang, Xinan (Holly), Wang, Bin, Cunningham, John M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460748/
https://www.ncbi.nlm.nih.gov/pubmed/26043758
http://dx.doi.org/10.1186/1755-8794-8-S2-S6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460748/
https://www.ncbi.nlm.nih.gov/pubmed/26043758
http://dx.doi.org/10.1186/1755-8794-8-S2-S6

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