Evaluation of multiplex ligation dependent probe amplification (MLPA) for identification of acute lymphoblastic leukemia with an intrachromosomal amplification of chromosome 21 (iAMP21) in a Brazilian population

BACKGROUND: An intrachromosomal amplification of chromosome 21 (iAMP21) defines a unique subgroup of B-cell precursor acute lymphoblastic leukemia (BCP-ALL). The finding of three or more extra copies of the RUNX1 gene by fluorescence in situ hybridization (FISH) is internationally used to define an...

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Detalles Bibliográficos
Autores principales: Fuka, Gerhard, Farias-Vieira, Tállita M., Hummel, Leticia, Blunck, Caroline B., Santoro, Júlio C., Terra-Granado, Eugênia, Conceição Barbosa, Thayana, Emerenciano, Mariana, Pombo-de-Oliveira, Maria S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460763/
https://www.ncbi.nlm.nih.gov/pubmed/26060508
http://dx.doi.org/10.1186/s13039-015-0147-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460763/
https://www.ncbi.nlm.nih.gov/pubmed/26060508
http://dx.doi.org/10.1186/s13039-015-0147-2

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