Conserved Functional Motifs and Homology Modeling to Predict Hidden Moonlighting Functional Sites

Moonlighting functional centers within proteins can provide them with hitherto unrecognized functions. Here, we review how hidden moonlighting functional centers, which we define as binding sites that have catalytic activity or regulate protein function in a novel manner, can be identified using tar...

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Detalles Bibliográficos
Autores principales: Wong, Aloysius, Gehring, Chris, Irving, Helen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460814/
https://www.ncbi.nlm.nih.gov/pubmed/26106597
http://dx.doi.org/10.3389/fbioe.2015.00082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460814/
https://www.ncbi.nlm.nih.gov/pubmed/26106597
http://dx.doi.org/10.3389/fbioe.2015.00082

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