A folded and immunogenic IgE-hyporeactive variant of the major allergen Phl p 1 produced in Escherichia coli

BACKGROUND: Group 1 grass pollen allergens are a major cause of allergic disease. Specific immunotherapy involving controlled administration of allergens can be used as a disease-modifying treatment for such disease. Recombinant allergen variants with reduced IgE binding capacity may be used as comp...

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Detalles Bibliográficos
Autores principales: Levin, Mattias, Otten, Harm, von Wachenfeldt, Claes, Ohlin, Mats
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460866/
https://www.ncbi.nlm.nih.gov/pubmed/26054338
http://dx.doi.org/10.1186/s12896-015-0150-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460866/
https://www.ncbi.nlm.nih.gov/pubmed/26054338
http://dx.doi.org/10.1186/s12896-015-0150-z

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