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A folded and immunogenic IgE-hyporeactive variant of the major allergen Phl p 1 produced in Escherichia coli
BACKGROUND: Group 1 grass pollen allergens are a major cause of allergic disease. Specific immunotherapy involving controlled administration of allergens can be used as a disease-modifying treatment for such disease. Recombinant allergen variants with reduced IgE binding capacity may be used as comp...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460866/ https://www.ncbi.nlm.nih.gov/pubmed/26054338 http://dx.doi.org/10.1186/s12896-015-0150-z |