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Targeting Wnt pathway in mantle cell lymphoma-initiating cells

BACKGROUND: Mantle cell lymphoma (MCL) is an aggressive and incurable form of non-Hodgkin’s lymphoma. Despite initial intense chemotherapy, up to 50 % of cases of MCL relapse often in a chemoresistant form. We hypothesized that the recently identified MCL-initiating cells (MCL-ICs) are the main reas...

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Detalles Bibliográficos
Autores principales: Mathur, Rohit, Sehgal, Lalit, Braun, Frank K., Berkova, Zuzana, Romaguerra, Jorge, Wang, Michael, Rodriguez, M. Alma, Fayad, Luis, Neelapu, Sattva S., Samaniego, Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460883/
https://www.ncbi.nlm.nih.gov/pubmed/26048374
http://dx.doi.org/10.1186/s13045-015-0161-1