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Insights into the Modulation of Dopamine Transporter Function by Amphetamine, Orphenadrine, and Cocaine Binding

Human dopamine (DA) transporter (hDAT) regulates dopaminergic signaling in the central nervous system by maintaining the synaptic concentration of DA at physiological levels, upon reuptake of DA into presynaptic terminals. DA translocation involves the co-transport of two sodium ions and the channel...

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Detalles Bibliográficos
Autores principales: Cheng, Mary Hongying, Block, Ethan, Hu, Feizhuo, Cobanoglu, Murat Can, Sorkin, Alexander, Bahar, Ivet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460958/
https://www.ncbi.nlm.nih.gov/pubmed/26106364
http://dx.doi.org/10.3389/fneur.2015.00134