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Brain tumor is a sequence-specific RNA-binding protein that directs maternal mRNA clearance during the Drosophila maternal-to-zygotic transition

BACKGROUND: Brain tumor (BRAT) is a Drosophila member of the TRIM-NHL protein family. This family is conserved among metazoans and its members function as post-transcriptional regulators. BRAT was thought to be recruited to mRNAs indirectly through interaction with the RNA-binding protein Pumilio (P...

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Detalles Bibliográficos
Autores principales: Laver, John D, Li, Xiao, Ray, Debashish, Cook, Kate B, Hahn, Noah A, Nabeel-Shah, Syed, Kekis, Mariana, Luo, Hua, Marsolais, Alexander J, Fung, Karen YY, Hughes, Timothy R, Westwood, J Timothy, Sidhu, Sachdev S, Morris, Quaid, Lipshitz, Howard D, Smibert, Craig A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460960/
https://www.ncbi.nlm.nih.gov/pubmed/25962635
http://dx.doi.org/10.1186/s13059-015-0659-4