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Ribosome profiling reveals translation control as a key mechanism generating differential gene expression in Trypanosoma cruzi

BACKGROUND: Due to the absence of transcription initiation regulation of protein coding genes transcribed by RNA polymerase II, posttranscriptional regulation is responsible for the majority of gene expression changes in trypanosomatids. Therefore, cataloging the abundance of mRNAs (transcriptome) a...

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Detalles Bibliográficos
Autores principales: Smircich, Pablo, Eastman, Guillermo, Bispo, Saloe, Duhagon, María Ana, Guerra-Slompo, Eloise P, Garat, Beatriz, Goldenberg, Samuel, Munroe, David J, Dallagiovanna, Bruno, Holetz, Fabiola, Sotelo-Silveira, Jose R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460968/
https://www.ncbi.nlm.nih.gov/pubmed/26054634
http://dx.doi.org/10.1186/s12864-015-1563-8