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Gene Expression Signatures Based on Variability can Robustly Predict Tumor Progression and Prognosis

Gene expression signatures are commonly used to create cancer prognosis and diagnosis methods, yet only a small number of them are successfully deployed in the clinic since many fail to replicate performance on subsequent validation. A primary reason for this lack of reproducibility is the fact that...

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Detalles Bibliográficos
Autores principales: Dinalankara, Wikum, Bravo, Héctor Corrada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460970/
https://www.ncbi.nlm.nih.gov/pubmed/26078586
http://dx.doi.org/10.4137/CIN.S23862