Cargando…

Angptl4 is upregulated under inflammatory conditions in the bone marrow of mice, expands myeloid progenitors, and accelerates reconstitution of platelets after myelosuppressive therapy

BACKGROUND: Upon inflammation, myeloid cell generation in the bone marrow (BM) is broadly enhanced by the action of induced cytokines which are produced locally and at multiple sites throughout the body. METHODS: Using microarray studies, we found that Angptl4 is upregulated in the BM during systemi...

Descripción completa

Detalles Bibliográficos
Autores principales: Schumacher, Anne, Denecke, Bernd, Braunschweig, Till, Stahlschmidt, Jasmin, Ziegler, Susanne, Brandenburg, Lars-Ove, Stope, Matthias B., Martincuks, Antons, Vogt, Michael, Görtz, Dieter, Camporeale, Annalisa, Poli, Valeria, Müller-Newen, Gerhard, Brümmendorf, Tim H., Ziegler, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460974/
https://www.ncbi.nlm.nih.gov/pubmed/26054961
http://dx.doi.org/10.1186/s13045-015-0152-2