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Magnetic resonance imaging of folic acid-coated magnetite nanoparticles reflects tissue biodistribution of long-acting antiretroviral therapy

Regimen adherence, systemic toxicities, and limited drug penetrance to viral reservoirs are obstacles limiting the effectiveness of antiretroviral therapy (ART). Our laboratory’s development of the monocyte-macrophage-targeted long-acting nanoformulated ART (nanoART) carriage provides a novel opport...

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Detalles Bibliográficos
Autores principales: Li, Tianyuzi, Gendelman, Howard E, Zhang, Gang, Puligujja, Pavan, McMillan, JoEllyn M, Bronich, Tatiana K, Edagwa, Benson, Liu, Xin-Ming, Boska, Michael D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461087/
https://www.ncbi.nlm.nih.gov/pubmed/26082630
http://dx.doi.org/10.2147/IJN.S83279