In Vivo Senescence in the Sbds-Deficient Murine Pancreas: Cell-Type Specific Consequences of Translation Insufficiency

Genetic models of ribosome dysfunction show selective organ failure, highlighting a gap in our understanding of cell-type specific responses to translation insufficiency. Translation defects underlie a growing list of inherited and acquired cancer-predisposition syndromes referred to as ribosomopath...

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Detalles Bibliográficos
Autores principales: Tourlakis, Marina E., Zhang, Siyi, Ball, Heather L., Gandhi, Rikesh, Liu, Hongrui, Zhong, Jian, Yuan, Julie S., Guidos, Cynthia J., Durie, Peter R., Rommens, Johanna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461263/
https://www.ncbi.nlm.nih.gov/pubmed/26057580
http://dx.doi.org/10.1371/journal.pgen.1005288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461263/
https://www.ncbi.nlm.nih.gov/pubmed/26057580
http://dx.doi.org/10.1371/journal.pgen.1005288

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