Mutation Analysis of the RAD51C and RAD51D Genes in High-Risk Ovarian Cancer Patients and Families from the Czech Republic

Recent studies have conferred that the RAD51C and RAD51D genes, which code for the essential proteins involved in homologous recombination, are ovarian cancer (OC) susceptibility genes that may explain genetic risks in high-risk patients. We performed a mutation analysis in 171 high-risk BRCA1 and B...

Descripción completa

Detalles Bibliográficos
Autores principales: Janatova, Marketa, Soukupova, Jana, Stribrna, Jana, Kleiblova, Petra, Vocka, Michal, Boudova, Petra, Kleibl, Zdenek, Pohlreich, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461297/
https://www.ncbi.nlm.nih.gov/pubmed/26057125
http://dx.doi.org/10.1371/journal.pone.0127711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461297/
https://www.ncbi.nlm.nih.gov/pubmed/26057125
http://dx.doi.org/10.1371/journal.pone.0127711

Ejemplares similares