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Membrane-Associated Transporter Protein (MATP) Regulates Melanosomal pH and Influences Tyrosinase Activity

The SLC45A2 gene encodes a Membrane-Associated Transporter Protein (MATP). Mutations of this gene cause oculocutaneous albinism type 4 (OCA4). However, the molecular mechanism of its action in melanogenesis has not been elucidated. Here, we discuss the role of MATP in melanin production. The SLC45A2...

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Detalles Bibliográficos
Autores principales: Bin, Bum-Ho, Bhin, Jinhyuk, Yang, Seung Ha, Shin, Misun, Nam, Yeon-Ju, Choi, Dong-Hwa, Shin, Dong Wook, Lee, Ai-Young, Hwang, Daehee, Cho, Eun-Gyung, Lee, Tae Ryong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461305/
https://www.ncbi.nlm.nih.gov/pubmed/26057890
http://dx.doi.org/10.1371/journal.pone.0129273