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First-in-man Study With Inclacumab, a Human Monoclonal Antibody Against P-selectin

Inclacumab, a novel monoclonal antibody against P-selectin in development for the treatment and prevention of atherosclerotic cardiovascular diseases, was administered in an ascending single-dose study as intravenous infusion to evaluate safety, pharmacokinetics, and pharmacodynamics. Fifty-six heal...

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Detalles Bibliográficos
Autores principales: Schmitt, Christophe, Abt, Markus, Ciorciaro, Cornelia, Kling, Dorothee, Jamois, Candice, Schick, Eginhard, Solier, Corinne, Benghozi, Renée, Gaudreault, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Cardiovascular Pharmacology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461388/
https://www.ncbi.nlm.nih.gov/pubmed/25714598
http://dx.doi.org/10.1097/FJC.0000000000000233