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First-in-man Study With Inclacumab, a Human Monoclonal Antibody Against P-selectin

Inclacumab, a novel monoclonal antibody against P-selectin in development for the treatment and prevention of atherosclerotic cardiovascular diseases, was administered in an ascending single-dose study as intravenous infusion to evaluate safety, pharmacokinetics, and pharmacodynamics. Fifty-six heal...

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Detalles Bibliográficos
Autores principales:	Schmitt, Christophe, Abt, Markus, Ciorciaro, Cornelia, Kling, Dorothee, Jamois, Candice, Schick, Eginhard, Solier, Corinne, Benghozi, Renée, Gaudreault, Jacques
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Journal of Cardiovascular Pharmacology 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461388/ https://www.ncbi.nlm.nih.gov/pubmed/25714598 http://dx.doi.org/10.1097/FJC.0000000000000233

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