Cargando…

Probucol Protects Against Atherosclerosis Through Lipid-lowering and Suppressing Immune Maturation of CD11c(+) Dendritic Cells in STZ-induced Diabetic LDLR(−/−) Mice

Probucol, an agent characterized by lipid-lowering and antioxidant property, retards atherosclerosis effectively. To test the hypothesis that probucol might act its antiatherosclerotic role by suppressing immune maturation of dendritic cells (DCs), 7-week-old LDLR(−/−) mice were rendered diabetic wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Hong, Jin, Xueting, Zhao, Jingjing, Dong, Zhen, Ma, Xin, Xu, Fang, Huang, Wei, Liu, George, Zou, Yunzeng, Wang, Keqiang, Hu, Kai, Sun, Aijun, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Cardiovascular Pharmacology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461394/
https://www.ncbi.nlm.nih.gov/pubmed/25714599
http://dx.doi.org/10.1097/FJC.0000000000000234