Orthogonal control of expression mean and variance by epigenetic features at different genomic loci

While gene expression noise has been shown to drive dramatic phenotypic variations, the molecular basis for this variability in mammalian systems is not well understood. Gene expression has been shown to be regulated by promoter architecture and the associated chromatin environment. However, the exa...

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Detalles Bibliográficos
Autores principales: Dey, Siddharth S, Foley, Jonathan E, Limsirichai, Prajit, Schaffer, David V, Arkin, Adam P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461400/
https://www.ncbi.nlm.nih.gov/pubmed/25943345
http://dx.doi.org/10.15252/msb.20145704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461400/
https://www.ncbi.nlm.nih.gov/pubmed/25943345
http://dx.doi.org/10.15252/msb.20145704

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