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Orthogonal control of expression mean and variance by epigenetic features at different genomic loci
While gene expression noise has been shown to drive dramatic phenotypic variations, the molecular basis for this variability in mammalian systems is not well understood. Gene expression has been shown to be regulated by promoter architecture and the associated chromatin environment. However, the exa...
Autores principales: | Dey, Siddharth S, Foley, Jonathan E, Limsirichai, Prajit, Schaffer, David V, Arkin, Adam P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461400/ https://www.ncbi.nlm.nih.gov/pubmed/25943345 http://dx.doi.org/10.15252/msb.20145704 |
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