A multi-label approach to target prediction taking ligand promiscuity into account

BACKGROUND: According to Cobanoglu et al., it is now widely acknowledged that the single target paradigm (one protein/target, one disease, one drug) that has been the dominant premise in drug development in the recent past is untenable. More often than not, a drug-like compound (ligand) can be promi...

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Detalles Bibliográficos
Autores principales: Afzal, Avid M, Mussa, Hamse Y, Turner, Richard E, Bender, Andreas, Glen, Robert C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461803/
https://www.ncbi.nlm.nih.gov/pubmed/26064191
http://dx.doi.org/10.1186/s13321-015-0071-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461803/
https://www.ncbi.nlm.nih.gov/pubmed/26064191
http://dx.doi.org/10.1186/s13321-015-0071-9

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