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A multi-label approach to target prediction taking ligand promiscuity into account
BACKGROUND: According to Cobanoglu et al., it is now widely acknowledged that the single target paradigm (one protein/target, one disease, one drug) that has been the dominant premise in drug development in the recent past is untenable. More often than not, a drug-like compound (ligand) can be promi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461803/ https://www.ncbi.nlm.nih.gov/pubmed/26064191 http://dx.doi.org/10.1186/s13321-015-0071-9 |