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Targeting ATM-deficient CLL through interference with DNA repair pathways

Chronic lymphocytic leukemia (CLL) is the most common form of leukemia in the Western world and accounts for approximately 30% of adult leukemias and 25% of non-Hodgkin lymphomas. The median age at diagnosis is 72 years. During recent years numerous genetic aberrations have been identified that are...

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Detalles Bibliográficos
Autores principales: Knittel, Gero, Liedgens, Paul, Reinhardt, Hans C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461826/
https://www.ncbi.nlm.nih.gov/pubmed/26113859
http://dx.doi.org/10.3389/fgene.2015.00207