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T helper cell mediated-tolerance towards fetal allograft in successful pregnancy

Trophoblast HLA-C antigens from paternal origins, which liken the trophoblast to a semiallograft, could be presented by the maternal APCs to the specific maternal CD4+ T helper cells, which could release various cytokines in response to these alloantigens. On the basis of the cytokines produced, the...

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Detalles Bibliográficos
Autores principales: Piccinni, Marie-Pierre, Lombardelli, Letizia, Logiodice, Federica, Kullolli, Ornela, Romagnani, Sergio, Le Bouteiller, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461901/
https://www.ncbi.nlm.nih.gov/pubmed/26064081
http://dx.doi.org/10.1186/s12948-015-0015-y