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Levo-tetrahydropalmatine attenuates mouse blood-brain barrier injury induced by focal cerebral ischemia and reperfusion: Involvement of Src kinase

The restoration of blood flow following thrombolytic therapy causes ischemia and reperfusion (I/R) injury leading to blood-brain barrier (BBB) disruption and subsequent brain edema in patients of ischemic stroke. Levo-tetrahydropalmatine (l-THP) occurs in Corydalis genus and some other plants. Howev...

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Detalles Bibliográficos
Autores principales: Mao, Xiao-Wei, Pan, Chun-Shui, Huang, Ping, Liu, Yu-Ying, Wang, Chuan-She, Yan, Li, Hu, Bai-He, Chang, Xin, He, Ke, Mu, Huan-Na, Li, Quan, Sun, Kai, Fan, Jing-Yu, Han, Jing-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461916/
https://www.ncbi.nlm.nih.gov/pubmed/26059793
http://dx.doi.org/10.1038/srep11155