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A novel method for evaluation and screening of caspase inhibitory peptides by the amino acid positional fitness score
BACKGROUND: Since caspases are key executioners of apoptosis in cases of severe diseases including neurodegenerative disorders such as Alzheimer's disease and Huntington's disease, and viral infection diseases such as AIDS and hepatitis, potent and specific inhibitors of caspases have clin...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2004
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC446194/ https://www.ncbi.nlm.nih.gov/pubmed/15154972 http://dx.doi.org/10.1186/1471-2210-4-7 |