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A novel method for evaluation and screening of caspase inhibitory peptides by the amino acid positional fitness score

BACKGROUND: Since caspases are key executioners of apoptosis in cases of severe diseases including neurodegenerative disorders such as Alzheimer's disease and Huntington's disease, and viral infection diseases such as AIDS and hepatitis, potent and specific inhibitors of caspases have clin...

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Detalles Bibliográficos
Autores principales: Yoshimori, Atsushi, Takasawa, Ryoko, Tanuma, Sei-ichi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC446194/
https://www.ncbi.nlm.nih.gov/pubmed/15154972
http://dx.doi.org/10.1186/1471-2210-4-7