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De-repressing LncRNA-Targeted Genes to Upregulate Gene Expression: Focus on Small Molecule Therapeutics

Non-protein coding RNAs (ncRNAs) make up the overwhelming majority of transcripts in the genome and have recently gained attention for their complex regulatory role in cells, including the regulation of protein-coding genes. Furthermore, ncRNAs play an important role in normal development and their...

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Detalles Bibliográficos
Autores principales: Fatemi, Roya Pedram, Velmeshev, Dmitry, Faghihi, Mohammad Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461991/
https://www.ncbi.nlm.nih.gov/pubmed/25405465
http://dx.doi.org/10.1038/mtna.2014.45